聚二甲基硅氧烷

Abstract(#br)Despite numerous preventive strategies on bacterial adhesion, pathogenic biofilm formation remained the major cause of medical device-related infections. Bacterial interference is a promising strategy that uses pre-established biofilms of benign bacteria to serve as live, protective coating against pathogen colonization. However, the application of this strategy to silicone urinary catheters was hampered by low adherence of benign bacteria onto silicone materials.

Abstract(#br)Cutaneous melanoma is an increasingly common and potentially lethal malignancy of melanocytes, the melanin producing cells normally located in the basal layer of the skin epidermis. Despite major advances in cancer chemotherapeutics and immunotherapy, the success in treating metastatic melanoma remains poor. The notion that cancer stem cells (CSCs) play a key role in melanoma progression is well received. Therefore, isolating and characterizing CSCs is of critical importance for designing new therapeutic strategies that target this unique tumor initiating cell sub-population.

Abstract(#br)The hydrophobic characteristics of PDMS and non-specific protein adsorption are major drawbacks for its application in biosensing. Here we have combined surface oxidation by plasma and chemical binding of polyvinyl alcohol (PVA) to obtain long-term stability of hydrophilic PDMS surfaces. Mercaptopropyltrimethoxisilane and aminopropyltrimethoxisilane were used as adhesives between the plasma-oxidized PDMS surface and the PVA, immobilized at room temperature.

Abstract(#br)A nano-composite membrane, created by coating a thin polysiloxane film to the surface of an anodic aluminum oxide (AAO) membrane, was directly coupled to the inlet system of a mass spectrometer. The gas-permeation properties of the polysiloxane nano-composite (PNC) membrane were compared to those of a conventional polydimethylsiloxane (PDMS) membrane over a range of hydrostatic pressures. Permeation of gases through the conventional PDMS membrane was reduced at high pressure by compression of the siloxane matrix.

Abstract(#br)We report characterization of polydimethylsiloxane (PDMS) pervaporation membranes prepared from various conditions using the small-angle neutron scattering (SANS). The PDMS membranes were prepared by cross-linking reactions between hydroxyl terminated polydimethylsiloxane (HPDMS) and polymethylhydrosiloxane with pendant hydride (PHMS). The radius of gyration ( R g ) of HPDMS and PHMS polymer chains determined from the SANS data analysis is found to be similar with the size of about 12\u003cce:hsp sp=\"0.25\"/\u003eÅ.

Abstract(#br)The objective of this work was to investigate the effect of polydimethylsiloxane (PDMS) molecular weights on the pervaporation performance and the confinement behavior of PDMS/ceramic composite membranes for the separation of ethanol from aqueous solutions by pervaporation. PDMS with three different molecular weights was used to prepare PDMS/ceramic composite membranes.

Abstract(#br)This article describes a versatile method for the modification of 2-hydroxyethyl cellulose (HEC) involving azide-alkyne cycloaddition reaction to impart neutral (ester) and ionic (carboxylic acid and 1 ry amine) functionalities. The synthetic approach involved, first the introduction of the azide functionality to HEC and then followed by its cycloaddition reaction with several alkyne terminated compounds: namely ethyl propiolate, 5-hexynoic acid and propargyl amine.

Abstract(#br)A novel in-needle microextraction (INME) for headspace sampling evaluated in this study has significantly higher extraction speed and the practical merits of a durable stainless steel needle to overcome some exposed fiber related drawbacks.

Abstract(#br)We report on an optical aptamer sensor for cocaine detection. The cocaine sensitive fluorescein isothiocyanate (FITC)-labeled aptamer underwent a conformational change from a partial single-stranded DNA with a short hairpin to a double-stranded T-junction in the presence of the target. The DNA minor groove binder Hoechst 33342 selectively bound to the double-stranded T-junction, bringing the dye within the Förster radius of FITC, and therefore initiating minor groove binder based energy transfer (MBET), and reporting on the presence of cocaine.

Abstract(#br)Solid-phase microextraction of hexachlorobenzene from water was implemented for the first time on a rotating disk coated with an octadecyl-bonded silica (C 18 ) sorptive phase. The results indicate that the sorption performance of this phase for the model analyte selected is similar to that observed using a rotating disk containing PDMS.