三维光刻

三次元立体露光法を用いて作製したがん細胞浸潤過程観察用マイクロ流体デバイス

ty10086 提交于 周四, 08/26/2021 - 13:01
This paper describes a microfluidic device for observation of cancer cell invasion induced by chemotaxis. The developed device has two main-channels, the channel filled with cell suspension and the channel filled with solution containing chemotactic factor. These channels are connected via tapered orifice structures to capture multiple cancer cells in it to form cell clusters. Observation of cell invasions affected by cell adhesions is possible with this device. The devices were fabricated by using three-dimensional lithography and PDMS(polydimethylsiloxane) molding.