The surface immobilization of galactose ligands on a PDMS substrate for use in primary rat hepatocyte culture
Abstract(#br)After isolation from a living organism, primary hepatocytes markedly change their morphology and lose specific functions. This study aimed to utilize a simple solution-phase surface modification method to fabricate a galactosylated polydimethylsiloxane (GAL-PDMS) substratum. Using both Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) and X-ray photoelectron spectroscopy (XPS) analysis, we demonstrated that the surface of PDMS was galactosylated.