SPME-GC/MS

New method to determination of naphthalene in ambient air using cold fiber-solid phase microextraction and gas chromatography–mass spectrometry

ty10086 提交于 周四, 08/26/2021 - 13:35
Abstract(#br)Naphthalene, a highly volatile polycyclic aromatic hydrocarbon (PAH), is classified as possibly carcinogenic to humans and can be found in various environments. This paper describes a cold fiber (CF) solid phase microextraction (SPME) sampling method coupled with gas chromatography/mass spectrometry (GC/MS) for determining naphthalene in ambient air. The method uses a 100\u003cce:hsp sp=\"0.25\"/\u003eμm polydimethylsiloxane (PDMS) fiber to generate gaseous standards using a permeation tube. The method shows good results for many validation parameters.

Rapid detection of sepsis in rats through volatile organic compounds in breath.

ty10086 提交于 周四, 08/26/2021 - 12:58
Sepsis is one of the main causes of death in adult intensive care units. The major drawbacks of the different methods used for its diagnosis and monitoring are their inability to provide fast responses and unsuitability for bedside use. In this study, performed using a rat sepsis model, we evaluate breath analysis with Ion Mobility Spectrometry (IMS) as a fast, portable and non-invasive strategy.;This study was carried out on 20 Sprague-Dawley rats. Ten rats were injected with lipopolysaccharide from Escherichia coli and ten rats were IP injected with regular saline.