Effect of wettability and surface roughness on the adhesion properties of collagen on PDMS films treated by capacitively coupled oxygen plasma
Abstract(#br)Direct chemical bonding of biomolecules to the surface of chemically inert polymers such as polydimethylsiloxane (PDMS) is not easily achieved. Therefore, pre-activation of such materials, followed by attachment of the biomolecule is necessary.(#br)This paper describes a procedure to functionalize a PDMS surface by oxygen-based plasma followed by the adhesion of collagen type I for the preparation of adhesive-free bilayer composite intended as skin substitute.