抗粘连

In vitro and in vivo evaluation of the antibacterial properties of a nisin-grafted hydrated mucin multilayer film

ty10086 提交于 周四, 08/26/2021 - 13:23
Abstract(#br)Microbial infection is one of the most serious problems in the field of medical devices, particularly in implants. Herein, we have designed and constructed a (mucin/poly(ethyleneimine)) n ((mucin/PEI) n ) multilayer film using a layer-by-layer self-assembly method and the grafting of antimicrobial peptides to enhance the bactericidal efficacy. Water contact angle measurements and atomic force microscopy images revealed that the hydrated multilayer film created a highly hydrophilic surface with a low roughness.

Bioinspired photocatalytic ZnO/Au nanopillar-modified surface for enhanced antibacterial and antiadhesive property

ty10086 提交于 周四, 08/26/2021 - 12:43
Abstract(#br)Biological contamination of surfaces is a thorny issue that brings series of adverse factors to the daily life and industrial manufacture. A dragonfly-wing-mimicking nanopillar array of ZnO/Au on Polydimethylsiloxane (PDMS-ZnO/Au) with two-fold bactericidal activity as well as the antiadhesive property has been developed. In this process, ZnO nanopillar is obtained using a hydrothermal method followed by the introduction of plasmonic gold nanoparticles (AuNPs) via a photo-reduction protocol.