Fiber-optic SERS microfluidic chip based on light-induced gold nano-particle aggregation
Abstract(#br)A novel optofluidic surface-enhanced Raman scattering (SERS) chip was specially designed and fabricated using polydimethylsiloxane (PDMS) and embedded with normal silica multi-mode optical fibers. Unlike in a conventional Raman detection configuration where an angle of 90° is commonly adopted, here the orientations of the excitation fiber and the collection fiber was set at such an obtuse angle so that the light beam from the excitation fiber can illuminate the endface, but is not within the acceptance angle of the collection fiber.