Implanted, inductively-coupled, radiofrequency coils fabricated on flexible polymeric material: Application to in vivo rat brain MRI at 7T

由 ty10086 提交于 周四, 08/26/2021 - 12:58
文章英文标题
Implanted, inductively-coupled, radiofrequency coils fabricated on flexible polymeric material: Application to in vivo rat brain MRI at 7T
正文
Graphical abstract [Display omitted] Highlights► Transmission line resonator principle is used to realize small inductively coupled planar coils. ► Implanted coils are coated with PDMS to ensure short term compatibility. ► Coating reduces the resonance frequency shift and the losses induced by the sample. ► The coil is implanted in rat brain and inductively coupled to an external coil. ► In vivo rat brain MRI is performed at 7T with the implanted microcoil.;AbstractCombined with high-field MRI scanners, small implanted coils allow for high resolution imaging with locally improved SNR, as compared to external coils. Small flexible implantable coils dedicated to in vivo MRI of the rat brain at 7T were developed. Based on the Multi-turn Transmission Line Resonator design, they were fabricated with a Teflon substrate using copper micromolding process and a specific metal–polymer adhesion treatment. The implanted coils were made biocompatible by PolyDimethylSiloxane (PDMS) encapsulation. The use of low loss tangent material achieves low dielectric losses within the substrate and the use of the PDMS layer reduces the parasitic coupling with the surrounding media. An implanted coil was implemented in a 7T MRI system using inductive coupling and a dedicated external pick-up coil for signal transmission. In vivo images of the rat brain acquired with in plane resolution of (150μm)2 thanks to the implanted coil revealed high SNR near the coil, allowing for the visualization of fine cerebral structures.
文章内容（英文）
Graphical abstract [Display omitted] Highlights► Transmission line resonator principle is used to realize small inductively coupled planar coils. ► Implanted coils are coated with PDMS to ensure short term compatibility. ► Coating reduces the resonance frequency shift and the losses induced by the sample. ► The coil is implanted in rat brain and inductively coupled to an external coil. ► In vivo rat brain MRI is performed at 7T with the implanted microcoil.;AbstractCombined with high-field MRI scanners, small implanted coils allow for high resolution imaging with locally improved SNR, as compared to external coils. Small flexible implantable coils dedicated to in vivo MRI of the rat brain at 7T were developed. Based on the Multi-turn Transmission Line Resonator design, they were fabricated with a Teflon substrate using copper micromolding process and a specific metal–polymer adhesion treatment. The implanted coils were made biocompatible by PolyDimethylSiloxane (PDMS) encapsulation. The use of low loss tangent material achieves low dielectric losses within the substrate and the use of the PDMS layer reduces the parasitic coupling with the surrounding media. An implanted coil was implemented in a 7T MRI system using inductive coupling and a dedicated external pick-up coil for signal transmission. In vivo images of the rat brain acquired with in plane resolution of (150μm)2 thanks to the implanted coil revealed high SNR near the coil, allowing for the visualization of fine cerebral structures.
来源出处
Journal|[J]Journal of Magnetic ResonanceVolume 224, 2012. PP 61-70
DOI
https://doi.org/10.1016/j.jmr.2012.09.003

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PDMS-微流控基质材料-PDMS/道康宁SYLGARD184-聚二甲基硅氧烷/0.5KG(组)

产品说明书PDF自助在线看：http://www.pdmshub.com/sih

信息更新：

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此链接为PDMS-微流控芯片/PDMS/道康宁SYLGARD184/小桶0.5KG装的链接。

一般性的产品性能参数表参考以下小桶装的参数：

微流控芯片/PDMS/道康宁SYLGARD184；微流控芯片/PDMS/道康宁SYLGARD184；微流控芯片/PDMS/道康宁SYLGARD184；

品牌型号：道康宁SYLGARD184

包装规格：0.5KG/罐[含有45.4g固化剂，总重量为0.5KG]

产品颜色：保质期限：36个月

存放环境说明：室温,阴凉处保存

备注说明：

美国道康宁道康宁SYLGARD 184硅橡胶是由液体组分组成的双组分套件产品，包括基本组分与固化剂。基本组分与固化剂按10:1重量比完全混合，中等粘度混合液的稠度与SAE 40机油相似。无论厚薄，混合液将固化成为具有韧性的透明弹性体，最适用于电子／电气方面的封装与灌封应用。 道康宁SYLGARD 184硅橡胶在25~150℃的温度范围内固化，无放热现象，无需二次固化。固化过程完成后，可立即在-55~200℃的温度范围内使用。 产品特性：低毒性，在常规的工业操作中，无特别的注意事项； 无溶剂或固化副产物， 固化时不放热；无需特殊的通风条件，不会产生腐蚀；固化时，收缩量小； 固化后， 透明具有弹性；抗震与减缓机械震动；振动的传递性能小；元件可裸视检查与易修补性； 环保性能；低吸水性，良好的耐辐射性能；高真空状态下的低漏气性； 优异的电性能；较大温度范围内的稳定性， 抗解聚；在-55~200℃范围内，甚至在密闭状态下保持弹性与柔韧性，性能稳定； 阻燃性，UL可燃性分级为94 V-1，温度等级：130℃ 产品用途： 道康宁SYLGARD 184硅橡胶在电气／电子的封装与灌封方面有广泛的应用。